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Abstract ID: 24-171
Comparing efficacy of Combined Intense Pulsed Light therapy and Low-Level Light therapy Versus Intense Pulsed Light for the treatment of dry eye disease : A retrospective study
Duangmontree Rojdamrongratana
Purpose
To compare the efficacy of Intense Pulsed Light therapy combined with Low-Level Light therapy Versus Intense Pulsed Light for the treatment of dry eye disease
Methods
Patients presenting with a dry eye disease(DED) with MGD and having recieved treatment with IPL or IPL with LLLT at Thammasat University Hospital between Febuary 2023 and November 2023 were included. The single IPL session and combined IPl and LLLT session was performed once weekly over 3 weeks. The end point was the mean difference of DEQ-5 score between baseline(0-14 days before the first session of the treatment) and 2 weeks after the last session. Data collection was done retrospectively. Statistical analysis was done using STATA 16.0
Results
: 51 patients were included (25 patients from IPL group, 26 patients from IPL with LLLT group). DEQ-5 score significantly decreased after the single IPL treatment and the combined IPL with LLLT treatment(P<0.001). Patients in the combine IPL with LLLT group showed significant improvement in DEQ-5 score compared with the single IPL group(-10.2±3.1 vs -7.8±2.1,P<0.05). No adverse effects were observed in both groups.
Conclusion
Both IPL and IPL with LLLT were safe and effective in improving ocular discomfort symptoms in MGD-related dry eye disease. However, the combined IPL with LLLT determined a greater improvement in symptoms.
Additional Authors
Napussorn Wankha – Thammasat Hospital
Nitchakarn Suksiriluk – Thammasat Hospital