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Abstract ID: 24-108
Oral Medications and Dry Eye Disease in Coronavirus Disease Survivors
Konstantin Gushansky
Purpose
This research aimed to explore the relationship between oral medications and the occurrence of Dry Eye Disease (DED) in individuals who survived COVID-19.
Methods
The study involved comparing two groups of COVID-19 survivors: those diagnosed with DED after hospitalization (n=52) and those without DED (n=1000). The analysis focused on examining the medication profiles of both groups.
Results
Several significant correlations emerged between specific medications and DED in COVID survivors. Notably, Lamotrigine exhibited a notable association with DED (3.9% vs. 0.9%, p=0.042). Conversely, Remdesivir showed a negative correlation (0% vs. 10.1%, p=0.016). Furthermore, Omeprazole (23.1% vs. 41%, p=0.01) and Pantoprazole (3.9% vs. 18.1%, p=0.009) displayed negative links with DED. Additionally, the study highlighted that polypharmacy was positively correlated with DED (p=0.047).
Conclusion
This study uncovers previously unrecognized associations between certain medications and DED among COVID-19 survivors. The findings emphasize the necessity for further investigation to better understand and manage ocular complications post-COVID.
Additional Authors
– Shaare Zedek Medical Center